25 January 2023 Candida albicans is an opportunistic yeast naturally occurring on our body. This yeast can become pathogenic causing candidiasis. Candidalysin, a peptide toxin secreted by the fungus, is involved in Candida becoming pathogenic the  mediates its translocation through intestinal epithelium causing serious infections. A recent study led by prof. Bernard Hube now shows that Candidalysin is also the driver of C. albicans-associated haemolysis. This process can be fully inhibited by two single domain antibodies. Link

15 March 2023 Big thanks to the group led by Anne Rios, who did an excellent job with establishing the mLSR-3D method for multispectral confocal 3D imaging. This nicely illustrates the excellent organ penetration of single domain antibodies and its suitability for imaging.

22 June 2022 Congrats to the team lead by professor Arjan Griffioen for their excellent study on targeting extracellular vimentin for cancer therapy. Link This study also features our anti-vimentin product Q60c, a single domain antibody that suits well for detection and microscopy.

30 May 2022 More than 1.5 million Dutch people suffer from osteoarthritis – a rheumatic disease of the joints that causes pain, stiffness and difficulty in moving. Since osteoarthritis is a condition that mainly occurs to elderly people, the number of patients will increase due to aging of the population. Currently there is no adequate treatment. The OAinject program is developing new diagnostic tools to determine the exact type of osteoarthritis someone has, in order to enable tailor-made treatments. In addition, the researchers are working on innovative ways to administer medicines in the joints over a longer period of time, gradually, as well as locally via a depot. In this way, the consortium wants to ensure that rheumatic patients can … Read more