All products will be sold for research purposes only, custom made and functionalized for your application.
Functionalization of these VHHs in order to generate high-end imaging agents can include directional conjugation to IRDye800CW (LI-COR), Hilyte dyes (Eurogentec), biotin and chelators like NOTA, and DOTA.
Contact sales@qvquality.com for more information on the possibilities of developing a high quality imaging agent for your molecule of interest.
Target Product Codes Suitable Applications References B7-H3 Q92c Detection BMP24 Q36c Noggin replacer Calpe et al. (2015) Calpe et al. (2016) BMP4 Q35c Detection, scavenging inhibition of BMPR1 binding Calpe et al. (2015) Calpe et al. (2016) CAIX Q29c Detection, imaging van Brussel et al. (2016) Kijanka et al. (2016) Candidalysin Q99c Q100c Detection, imaging, neutralization Mogavero et al. (2021) C5 Q101c Q102c Detection, inhibition Struijf et al. (2023) CD63 Q111 Q112 ELISA, FC CD80 Q98c Detection, imaging CD163 Q68c Detection, imaging CXCR4 Q84c Q85c Detection, ligand competition, imaging van Hout et al. (2018) DC-SIGN Q51c Detection, imaging EGFR Q44c Q86c Detection, ligand competition, imaging Hofman et al. (2008) EpCAM Q66c Detection Fc-domain Q96c Detection, capturing Fibrinogen Q113 – ELISA, FC Glycoprotein 1b alpha Q114 – ELISA, FC, inhibition Glycoprotein VI Q115 Q116 ELISA, FC, inhibition HER2 Q17c Detection, imaging Kijanka et al. (2013) Kijanka et al. (2016) HIV gp120 Q1c Q9c Detection, neutralization McCoy et al. (2012) Strokappe et al. (2012) HIV gp41 Q8c Q54c Detection, neutralization Lutje Hulsik et al. (2013) HIV p24 Q76c Q76Bc Detection Gray E.R. et al. (2017) IRDye800 Q93c Detection, capturing ITGB1 Q75c Detection cMet Q22c Detection, ligand competition, imaging Heukers et al. (2014) Heukers et al. (2018) NCAM1 Q55c Detection, imaging van Ineveld et al., (2021) Dekkers et al. (2022) PD-L2 Q90c Detection P-Selectin Q117 ELISA, FC, inhibition SARS-CoV-2 Q103c Q104c Detection, neutralization TfR Q52c Detection, imaging Emmerson et al. (2013) uPAR Q88c Detection, imaging Vimentin Q60c Detection, imaging Van Beijnum et al. (2020) VLA3 Q49c Detection, imaging Groot et al. (2009) vWF Q118 – ELISA, FC Rabbit anti VHH QE19 VHH detection in ELISA, WB, IHC, IF, FC Pronk et al. (2021) van Lith et al. (2022)
