QVQ sells products for research purposes. The following products are available off-the-shelf and can be functionalized as specified below.
Contact sales@qvquality.com for more information.
Target Product Application References VHH QE19 VHH detection in ELISA, WB, IHC, IF, FC Pronk et al. (2021) van Lith et al. (2022) ACKR3 Q123 Q125 Q126c Detection, ligand competition, imaging Song et al. (2021) Kleist et al. (2022) B7-H3 Q92c Detection BMP2/ 4 Q36c Noggin replacer Calpe et al. (2015) Calpe et al. (2016) BMP4 Q35bc Detection, scavenging inhibition of BMPR1 binding Calpe et al. (2015) Calpe et al. (2016) C3 Q122c ELISA C3b Q119c ELISA C5 Q101c Q102c Detection, inhibition Struijf et al. (2023) C5b6 Q120c Q127c ELISA, inhibition CAIX Q29c Detection, imaging van Brussel et al. (2016) Kijanka et al. (2016) Candidalysin Q99c Q100c Detection, imaging, neutralization CCR2 Q124c Detection, imaging CD63 Q111 Q112 ELISA, FC CD80 Q98c Detection, imaging CD163 Q68c Detection, imaging Complement factor B Q121c ELISA CXCR4 Q84c Q85c Detection, ligand competition, imaging van Hout et al. (2018) DC-SIGN Q51c Q94c Detection, imaging Bouma et al., 2024 EGFR Q44c Q86c Detection, ligand competition, imaging Hofman et al. (2008) EpCAM Q66c Detection Fc-domain Q96c Detection, capturing Fibrinogen Q113 ELISA, FC Glycoprotein 1b alpha Q114 ELISA, FC, inhibition Glycoprotein VI Q115 Q116 ELISA, FC, inhibition HER2 Q17c Detection, imaging Kijanka et al. (2013) Kijanka et al. (2016) HIV gp120 Q1c Q9c Detection, neutralization McCoy et al. (2012) Strokappe et al. (2012) HIV gp41 Q8c Q54c Detection, neutralization Lutje Hulsik et al. (2013) HIV p24 Q76bc Detection Gray E.R. et al. (2017) IRDye800 Q93c Detection, capturing ITGB1 Q75c Detection cMet Q22c Detection, ligand competition, imaging Heukers et al. (2014) Heukers et al. (2018) NCAM1 Q55c Detection, imaging van Ineveld et al., (2021) Dekkers et al. (2022) PD-L2 Q90c Detection P-Selectin Q117 ELISA, FC, inhibition SARS-CoV-2 Q103c Q104c Detection, neutralization TfR Q52c Detection, imaging Emmerson et al. (2013) Tubulin Q128c ELISA, detection, imaging Mikhaylova et al. (2015) uPAR Q88c Detection, imaging Vimentin Q60c Detection, imaging Van Beijnum et al. (2020) VLA3 Q48c Detection, imaging Groot et al. (2009) vWF Q118 ELISA, FC
Possible functionalizations of these sdAbs include genetic fusions and site-directed conjugations via maleimide-thiol reactions to the following molecules.
Fluorophores
HiLyte488
HiLyte555
HiLyte647
IRDye 680RD
IRDye 800CW
Various ATTO dyes
Proteins
HRP
Luciferases
Fluorophores
Other
Biotin
Peptides
Oligonucleotides
In addition, we offer custom conjugations to your sdAb and label of interest. Contact us for more information.
