01 July 2025
A decade ago, the groups of Lukas Kapitein at Universiteit Utrecht University and Helge Ewers at Freie Universität Berlin showed that superresolution imaging with antibodies can be enhanced by using smaller probes like single-domain antibodies (sdAb).
For example, the resolution of single molecule localization microscopy (SMLM) images of Tubulin could be substantially improved by using anti-tubulin sdAbs.
QVQ now offers this anti-tubulin sdAb as purified recombinant protein for research purposes (product Q128c). Q128c has an unpaired thiol in its C-terminal tag for directional labelling.
QVQ can deliver Q128c either as naked sdAb or conjugated to a fluorophores for normal and super resolution imaging.
