Characterization of single-domain antibodies.
Standard quality control consists of UV-Vis spectroscopy and SDS-PAGE analysis for determination of protein concentration, integrity, and sample purity. Additionally, the composition of the native sample can be further analyzed by size-exclusion chromatography (SEC).
Characterizations using other techniques can be performed in collaboration with partners. These include:
- Dynamic Light Scattering (DLS)
- Affinity-capture self-interaction nanoparticle spectroscopy (AC-SINS)
- Hydrophobic interaction chromatography (HIC)
- Capillary Electrophoresis Sodium Dodecyl Sulfate (CE-SDS)
- Intact Protein Mass Spectometry (MS)