Tubulin proteins are essential components of the cytoskeleton in cells. Tubulin exists mainly as two closely related globular proteins, α-tubulin and β-tubulin, which polymerize into dynamic microtubules. Microtubules are involved in various cellular processes, including cell division, intracellular transport, and maintenance of cell shape. Additionally, tubulin’s role in intracellular transport is vital for the movement of organelles and vesicles within cells. Understanding tubulin function is key to developing treatments for diseases like cancer, where cell division is dysregulated.
Source:
Recombinant monoclonal single-domain antibody (Lama glama), purified from S. cerevisiae using affinity chromatography. Immunization with MCF7 cells and phage-display selection on bovine brain tubulin using total elution.
Product details.
Specificity:
Tubulin
Formulation:
0.2 µm filtered solution in PBS. The products are equiped with a C-terminal C-Direct tag with an unpaired cysteine for directional conjugation.
Mol. Weight:
14.6 kDa
Ext. Coeff. (ε):
28545 M-1cm-1
A280 at 1g/L:
1.95
Storage:
Shipped on blue ice. Store at 4˚C or -20˚C (aliquots). Addition of 0.02% sodium azide is optional.
